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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: USP1 All Species: 28.48
Human Site: S575 Identified Species: 56.97
UniProt: O94782 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O94782 NP_001017415.1 785 88207 S575 S T K P T N D S Y G L F A V V
Chimpanzee Pan troglodytes XP_513450 785 88166 S575 S T K P T N D S Y G L F A V V
Rhesus Macaque Macaca mulatta XP_001085195 784 88189 S574 S T K P T N D S Y G L F A V V
Dog Lupus familis XP_865460 785 88368 S575 S T K P T N D S Y G L F A V V
Cat Felis silvestris
Mouse Mus musculus Q8BJQ2 784 87438 S574 S T K P T N D S Y G L F A V V
Rat Rattus norvegicus Q569C3 784 87311 S575 S T K P T N D S Y G L F A V V
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus NP_001026461 794 88314 Y586 T K P T N D T Y G L F A V V M
Frog Xenopus laevis Q52KZ6 370 42846 T184 Q G T L T N E T R C L T C E T
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera NP_001128140 646 73202 A460 Q L K R F S T A A G S M E K I
Nematode Worm Caenorhab. elegans P34547 426 48259 C240 Q N T S I S H C L R V F S E T
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays NP_001146737 368 41784 T182 Q G I L T N E T R C L R C E T
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q8LAM0 365 41828 T179 Q G I L T N E T R C L R C E T
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.6 97.3 94.3 N.A. 88.5 88.6 N.A. N.A. 73.1 20.5 N.A. N.A. N.A. 21.7 22.5 N.A.
Protein Similarity: 100 100 98.5 96.5 N.A. 93.2 92.6 N.A. N.A. 82.4 32.8 N.A. N.A. N.A. 38.8 36.4 N.A.
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. N.A. 6.6 20 N.A. N.A. N.A. 13.3 6.6 N.A.
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. N.A. 26.6 33.3 N.A. N.A. N.A. 33.3 26.6 N.A.
Percent
Protein Identity: N.A. 21.4 N.A. 20.3 N.A. N.A.
Protein Similarity: N.A. 31.5 N.A. 30.4 N.A. N.A.
P-Site Identity: N.A. 20 N.A. 20 N.A. N.A.
P-Site Similarity: N.A. 33.3 N.A. 33.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 9 9 0 0 9 50 0 0 % A
% Cys: 0 0 0 0 0 0 0 9 0 25 0 0 25 0 0 % C
% Asp: 0 0 0 0 0 9 50 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 25 0 0 0 0 0 9 34 0 % E
% Phe: 0 0 0 0 9 0 0 0 0 0 9 59 0 0 0 % F
% Gly: 0 25 0 0 0 0 0 0 9 59 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 9 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 17 0 9 0 0 0 0 0 0 0 0 0 9 % I
% Lys: 0 9 59 0 0 0 0 0 0 0 0 0 0 9 0 % K
% Leu: 0 9 0 25 0 0 0 0 9 9 75 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 9 0 0 9 % M
% Asn: 0 9 0 0 9 75 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 9 50 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 42 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 9 0 0 0 0 25 9 0 17 0 0 0 % R
% Ser: 50 0 0 9 0 17 0 50 0 0 9 0 9 0 0 % S
% Thr: 9 50 17 9 75 0 17 25 0 0 0 9 0 0 34 % T
% Val: 0 0 0 0 0 0 0 0 0 0 9 0 9 59 50 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 9 50 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _